• Diagnosis of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase (MPO) deficiency; monitoring chimerism and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase function posthematopoietic cell transplantation
• Assessing residual NADPH oxidase activity pretransplant
• Identification of carrier females for X-linked CGD; assessment of changes in lyonization with age in carrier females

Dk green Sodium heparin (Na hep), no gel

Allina facility special instructions:

1. Due to special requirements for collection, this test requires pathologist pre-approval by calling Client Services at (612) 863-4678. 
2. If approved, collection must be scheduled in advance and is only performed at the Abbott-Northwestern, Mercy and United Hospital sites.
3. This test is performed by Mayo Clinic Laboratories (MCL). If it is more convenient for them, patients may go to a Mayo facility for specimen collection.

• Both a patient and control specimen from an unrelated, healthy donor are required.
  • Control specimen should be collected from an Allina Health employee.
• Collect specimens Mo - Th only. No weekends or holidays.

Collection instructions:

1. Draw a control specimen from a normal (healthy), unrelated person within an hour of the patient.
2. Immediately following collection, mix sample thoroughly by gently inverting 5 - 10 times, to prevent clotting
3. Label clearly on outermost label normal control.

It is recommended that specimens arrive within 24 hours of specimen collection.

Dk green Sodium heparin (Na hep), no gel

Ambient (strict) – 48 hours

Refrigerated - NO

Frozen - NO

• Gross hemolysis
• Gross lipemia

Flow cytometry

The appropriate age-related reference values for Absolute Neutrophil Count will be provided on the report.