• All IHC stains will include a positive control tissue

• Chymotrypsin can be useful in classifying carcinomas of the pancreas by identifying cells with acinar differentiation
• Carcinomas with ductal or endocrine differentiation will generally be negative for chymotrypsin

Prepare a formalin-fixed, paraffin-embedded (FFPE) tissue block

Formalin-fixed, paraffin-embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• Chymotrypsin is an antibody that reacts with human pancreatic chymotrypsin, made by the acinar cells of the exocrine pancreas
• This antibody does not cross react with human pancreatic trypsin

 
Staining pattern

• Granular cytoplasmic