Therapeutic drug management
Trough levels are most reproducible
Dk green heparin (Li or Na), no gel
Immediatley following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting
Transfer vial/tube with cap - 12mL (LabCorp)
Ambient (preferred) - <3 days
Refrigerated - 2 weeks
Frozen - 6 weeks
Gel-barrier tubes are not recommended
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Clobazam: 30 - 300 ng/mL
Desmethylclobazam: 300 - 3000 ng/mL