• All IHC stains will include a positive control tissue

• MPO labels granulocytes (including promyelocytes, myelocytes, metamyelocytes, and mature neutrophils)
• MPO does not recognize lymphocytes or eosinophils
• Monocytes are negative for MPO, or contain small areas of positivity
• MPO is most useful in the differentiated of diagnosis of NHL vs. chloroma/granulocytic sarcoma

Submit a formalin-fixed, paraffin embedded tissue block

Formalin-fixed, paraffin embedded (FFPE) tissue block

FFPE tissue section mounted on a charged, unstained slide

Ambient (preferred)

• Unlabeled/mislabeled block
• Insufficient tissue
• Slides broken beyond repair

Immunohistochemical staining and microscopic examination

If requested, an interpretive report will be provided

Specifications

• MPO recognizes the enzyme by the same name

Staining pattern

• Granular cytoplasmic based staining