Eslicarbazepine metabolite-14234

Test info

  
Eslicarbazepine metabolite
  
14234
  
LAB14234
  
ESLICARBMET
  
Aptiom
ESL
Exalief
Zebinix
  

Therapeutic drug monitoring.

Eslicarbazepine is an aromatic anticonvulsant that is used in combination with other antiepileptic agents as therapy of partial onset seizures.

Specimen

  
Serum
  

Red serum vial/tube, 5 mL

  
1.0 mL
  
0.3 mL
  
  • Draw trough levels immediately prior to next dose.
  • Do not use a gel barrier tube.
    • The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel.
    • Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
  
  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  

Transfer vial/tube with cap - 12mL (LabCorp)

  
EDTA plasma
  

Lavender (EDTA), 4mL

  

Immediatley following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  
  1. Spin within two (2) hours of sample collection
  2. Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as EDTA plasma
  

Ambient (preferred) - 14 days

Refrigerated  - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

  
  • Gel barrier tube
  • Gross lipemia
  • Hemolysis
  • Icteric specimen

Performance

  
LabCorp Burlington (716931): R-LC
  
Mo - Fr, cut-off 10:30 am
  
2 - 4 days
  

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS-MS)

Clinical and Interpretive info

  

See report

Billing

  
G0480
  
Yes
  

Medical necessity

Tracking

  
04/05/2019
  
12/31/2023
  
12/31/2023