Complement C1 esterase inhibitor, functional-13378

Test info

  
Complement C1 esterase inhibitor, functional
  
13378
  
LAB13378
  
C1INF
  
C1
C1 esterase inhibitor
C1 Inactivator
C1 inhibitor
Esterase inhibitor
Hereditary angioneurotic edema test
  

Enzyme immunoassay (EIA) to measure functional activity. This method provides C1 esterase function activity as a percentage of mean normal activity.

  

Esterase inhibitor is decreased in hereditary angioneurotic edema. Functional level will be decreased when concentration of inhibitor is decreased or inhibitor is nonfunctional.

Specimen

  
Serum
  

Red serum vial/tube, 5 mL

  
0.5 mL
  
0.1 mL
  
  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum
  4. Freeze

To avoid delays in turnaround time when requesting multiple tests on frozen samples, submit a separate frozen aliquot for each test requested.

  

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

  
EDTA plasma
  

Lavender (EDTA), 4mL

  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

  
  1. Spin
  2. Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as EDTA plasma, within two (2) hours of sample collection
  3. Freeze
  
Serum
Frozen (preferred)
Ambient - 6 hours

EDTA plasma
Frozen (preferred)
Ambient - 24 hours
 
  
  • Plasma other than EDTA
  • Thawed or non-frozen sample

Performance

  
LabCorp Burlington (120220): R-LC
  
Mo, We, Fr
  
2 - 5 days
  

Enzyme immunoassay (EIA)

Clinical and Interpretive info

  
% of mean normal activity
Abnormal: <41%
Equivocal:    41% - 67%
Normal:     >67%

Billing

  
86161
  
Result 48494-9

Tracking

  
03/29/2019
  
11/15/2019
  
12/29/2023