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ImmuKnow-14469

Test info

Test name:

ImmuKnow

Test number:

14469

Excellian order number:

LAB14469

Abbreviation:

ICF

Alternate names:

Cellular Function Assay (involving stimulation and detection of a biomarker)
Cylex Immune Assay
Immuno Test
Immunosuppression Level Assay
Immune cell function

Useful for:

This test is a transplant physician's means of obtaining and monitoring information about immune status. ImmuKnow® measures the adenosine triphosphate (ATP) response of stimulated peripheral blood lymphocytes.

Specimen

Specimen type:

Sodium heparin (Na hep) whole blood

Collection container:

Two (2) Dk green Sodium heparin (Na hep), no gel

Volume:

8 mL

Minimum volume:

4 mL

Collection instructions:

Collect Mo – Th only
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

Processing instructions:

Do not spin
Submit original tube

Transport container:

Two (2) Dk green Sodium heparin (Na hep), no gel

Transport and stability:

Ambient (strict) – 30 hours

Refrigerated - NO

Frozen - NO

Specimen must be transported to the Allina Health Central Laboratory, in a STAT bag, on the day of collection. Specimen must arrive at AHL by 3:30pm to facilitate shipping to the performing laboratory.

Reason for rejection:

Specimen chilled, refrigerated, or frozen
Specimen >30 hours since collection
Clotted specimen
Hemolysis
Lithium heparin whole blood received

Performance

Performing lab:

LabCorp (176120): R-LC

Days set up:

Mo - Th

TAT:

2 - 4 days

Method:

PHA stimulation ATP luciferase assay

Clinical and Interpretive info

Reference ranges:

<226 ng/mL ATP	Low Immune Cell Response
226 – 524 ng/mL ATP	Moderate Immune Cell Response
>524 ng/mL ATP	Strong Immune Cell Response

Billing

CPT codes:

86352

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Tracking

Date created:

06/16/2021

Revised date:

09/29/2026

Review date:

09/29/2026