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Antiadrenal Antibodies, Quantitative-994

Test info

Test name:

Antiadrenal Antibodies, Quantitative

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Adrenal antibodies, serum
Antiadrenal cortex antibodies

Useful for:

Evaluate for adrenal insufficiency and Addison disease

Specimen

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

0.6 mL

Minimum volume:

0.3 mL

Collection instructions:

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for minimum of 30 minutes
Spin within two (2) hours of sample collection

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (strict)

Refrigerated - NO

Frozen - NO

Performance

Performing lab:

LabCorp Burlington (082024): R-NX

Days set up:

Tu, Th

TAT:

2 - 4 days

Method:

Indirect fluorescent antibody (IFA)

Clinical and Interpretive info

Reference ranges:

Negative: < 1:10

Clinical information:

Serum antibodies to adrenal cortical cells, usually of all three zones, are seen in 60% of patients with idiopathic Addison disease. They are present in only 5% to 17% of patients with tuberculous, fungal, or metastatic destruction of the adrenals, and in 38% of unclassified cases. Antiadrenal antibodies are also present in such apparently unrelated processes as idiopathic hypoparathyroidism (28% of cases) and Hashimoto disease (7%).

Billing

CPT codes:

86255

LOINC code:

Result 5043-5

Tracking

Date created:

06/06/2019

Revised date:

06/13/2023

Review date:

06/05/2023