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Kelch-Like Protein 11 Antibody, Cell Binding Assay, Serum-994

Test info

Test name:

Kelch-Like Protein 11 Antibody, Cell Binding Assay, Serum

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Kelch 11
Kelch-like protein 11
KLH11

Tests included:

If the cell binding antibody result is reactive, then the immunofluorescence titer assay will be performed at an additional charge.

Useful for:

Positivity for Kelch-like protein 11 (KLHL11)-IgG is indicative of a paraneoplastic neurological syndrome. Positivity indicates a high likelihood of finding a testicular cancer. A rigorous search for cancer should be initiated after KLHL11 autoimmunity is confirmed.

Specimen

Patient preparation information:

For optimal antibody detection, specimen collection is recommended before starting immunosuppressant medication or intravenous immunoglobulin (IVIg) treatment.

Specimen type:

Serum

Collection container:

Red serum vial/tube, 5 mL

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection
Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum

Transport container:

Screw cap transfer vial/tube (Mayo T914)

Transport and stability:

Refrigerated (preferred) - 28 days

Ambient - 72 hours

Frozen - 28 days

Reason for rejection:

Gross hemolysis, lipemia or icterus

Performance

Performing lab:

Mayo Clinic Laboratories (KLHCS); R-NX

Days set up:

Mo - Su

TAT:

3 - 5 days

Method:

Cell-Binding Assay (CBA)

Clinical and Interpretive info

Reference ranges:

Negative

Billing

CPT codes:

0432U

Tracking

Date created:

08/24/2026

Review date:

08/24/2026