Monitor chronic exposure to arsenic
Patient must avoid all seafood for 72 hours prior to collection. Seafood consumption two to three days prior to specimen collection can markedly elevate levels of total arsenic in urine. This dietary form of arsenic is nontoxic and is comprised primarily of arsenobetaine and arsenocholine. Inorganic arsenic is used for industrial exposure monitoring.
Screw cap plastic container (sterile)
24 hr urine collection container, no additive
Do not use preservatives. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing.
24 hr urine collection container, no additive
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
Inductively coupled plasma-mass spectrometry (HPLC/ICP-MS)
Environmental exposure
Total arsenic: 0−9 μg/L, 0−50 μg/24 hours
Inorganic arsenic: < 20 μg/L
Occupational exposure
BEI®, inorganic arsenic plus methylated metabolites (sampling time is end of work week): 35 μg/L creatinine
Sampling time is the end of the work week for industrial exposure monitoring. Metals with timing "end of work week" (meaning four or five consecutive working days with exposure) are eliminated with half-lives longer than five hours. Such metals accumulate in the body during the work week; therefore, their timing is critical in relation to previous exposures.