Fluconazole, serum or plasma-994
Test info
Fluconazole, serum or plasma
994
LAB994
MSO
Diflucan
Treatment of candidiasis, cryptococcal meningitis, and antifungal prophylaxis in allogeneic bone marrow transplant recipients.
Specimen
Serum
1.0 mL
0.5 mL
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
EDTA plasma
Immediatley following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
- Spin within two (2) hours of sample collection
- Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as EDTA plasma
Transfer vial/tube with cap - 12mL (LabCorp)
Refrigerated (preferred) - 14 days
Ambient - 14 days
Frozen - 14 days
- Serum from gel-barrier tubes is not acceptable and will be rejected
Performance
LabCorp Burlington (700485): R-NX
Mo - Fr
3 - 7 days
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Clinical and Interpretive info
The average peak concentration in fasted patients one to two hours after administration of a single oral 400mg dose of Fluconazole was 6.72 µg/mL (range 4.12 - 8.08).
No relationship between plasma concentrations and efficacy or toxicity has been identified for Fluconazole, however, exposure may be altered in instances of renal dysfunction or renal replacement therapy.
Billing
80299
Result 10987-6
Tracking
10/09/2019
10/14/2019
12/27/2023