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Glycine Receptor Alpha1 IgG, Cell Binding Assay, Serum-994

Test info

Test name:

Glycine Receptor Alpha1 IgG, Cell Binding Assay, Serum

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Glycine
GlyR
alpha 1 subunit
GlyRa1
GLRA1
Glycine Alpha1 LCBA, S

Useful for:

Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using serum specimens.

Specimen

Specimen type:

Serum

Collection container:

Red serum vial/tube - 5 mL

Volume:

1.0 mL

Minimum volume:

1.0 mL

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection
Transfer the serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum

Transport container:

Screw cap transfer vial/tube (Mayo T914)

Alternate collection container:

Gold serum separator (SST) tube

Alternate collection instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection

Alternate transport container:

Gold serum separator (SST) tube

Transport and stability:

Refrigerated (preferred) - 28 days

Ambient - 72 hours

Frozen - 28 days

Specimen retention time:

28 days

Reason for rejection:

Gross hemolysis
Gross lipemia
Gross icterus

Performance

Performing lab:

Mayo Clinic Laboratories (GLYCS): R-NX

Days set up:

Thu

TAT:

5 - 10 days

Method:

Live Cell-Binding Assay (LCBA)

Clinical and Interpretive info

Reference ranges:

Negative

Cautions:

Negative results do not exclude autoimmune stiff-person spectrum or cancer.

Billing

CPT codes:

86255

Tracking

Date created:

01/03/2023

Revised date:

12/20/2025

Review date:

12/20/2025