To measure the drug level in order to monitor therapeutic level and/or diagnose under-dosage or potential toxicity.
Immediatley following collection, mix sample by gentle inversion 3 - 4 times to prevent clotting
Ambient (preferred) - 7 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles: stable x3
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
See report
Although routine monitoring is not needed, there are a number of clinical circumstances in which clinicians want or need to know a patient's Apixaban level. Levels can be accurately and precisely measured using either a chromogenic anti-Xa assay or LC/MS-MS.