BTK Inhibitor Acquired Resistance Panel-994

Test info

  
BTK Inhibitor Acquired Resistance Panel
  
994
  
LAB994
  
MSO
  
BTK
BTK acquired resistance
  

This panel detects mutations in BTK and PLC-gamma-2 which are associated with acquired ibrutinib resistance in certain B-cell neoplasms. This panel is appropriate for patients with B-cell neoplasms who have relapsed and/or show acquired (secondary) resistance after an initial response to BTK (Bruton tyrosine kinase) inhibitors.

Specimen

  
Whole blood
  
  
5 mL
  
3 mL
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Lavender (EDTA), 4mL

  
Bone marrow
  
2 mL (min vol 0.5 mL)
  

Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

  

Refrigerated - 72 hours

  
  • Clotted specimens
  • Frozen specimens

Performance

  
NeoGenomics; R-NX
  
10 days
  

Molecular

Clinical and Interpretive info

Billing

  
81233; 81320
81479
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Molecular Medicare billing request

Tracking

  
03/21/2024
  
05/15/2024
  
03/21/2024