Human epididymis protein 4-994
Test info
Epidymis
Epidydimis
Epydidymis
HE4 Epidydimis
The assay is used as an aid in monitoring recurrence or progressive disease in patients with epithelial ovarian cancer. Serial testing for patient HE4 assay values should be used in conjunction with other clinical findings used for monitoring ovarian cancer. Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.
Specimen
This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R).
It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Submission of the minimum volume does not allow for repeat testing
Immediately following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
Refrigerated (preferred) - 14 days
Ambient - 5 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
Performance
Electrochemiluminescence Immunoassay (ECLIA)
Clinical and Interpretive info
|
Gender |
Range (pmol/L) |
|
Male |
Not established |
|
Female |
|
|
0 - 39 years |
0.0 - 61.2 |
|
40 - 49 years |
0.0 - 63.6 |
|
50 - 59 years |
0.0 - 105.2 |
|
60 - 69 years |
0.0 - 96.5 |
|
> 69 years |
0.0 - 96.9 |