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Carbamazepine & epoxide, free and total-2755

Test info

Test name:

Carbamazepine & epoxide, free and total

Test number:

2755

Excellian order number:

LAB2755

Abbreviation:

CFT

Alternate names:

Carbatrol®
CBZ
Epitol®
Epoxide
Tegretol®

Tests included:

Carbamazepine
Carbamazepine-10,11-epoxide
Carbamazepine, unbound
Carbamazepine epoxide, unbound

Useful for:

Therapeutic drug management

Specimen

Specimen type:

Serum

Collection container:

Red serum vial/tube, 10 mL

Volume:

5.0 mL

Minimum volume:

1.2 mL

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin
Transfer serum to a Serum/plasma transfer vial/tube (MedTox), labelled as serum, within two (2) hours of sample collection

Transport container:

Serum/plasma transfer vial/tube (MedTox)

Alternate specimen type:

Heparin plasma

Alternate collection container:

Dk green heparin (Li or Na), no gel - Two (2)

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

Alternate processing instructions:

Spin
Transfer plasma to a Serum/plasma transfer vial/tube (MedTox), labelled as the appropriate plasma type, within two (2) hours of sample collection

Transport and stability:

Refrigerated (preferred)

Ambient - 3 days

Frozen - OK

Reason for rejection:

Gel barrier tubes

Performance

Performing lab:

MedTox Laboratories (2153): R-MX

Days set up:

Daily

TAT:

2 - 3 days

Method:

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Clinical and Interpretive info

Reference ranges:

Carbamazepine, total: 4.0 - 12.0 µg/mL
Carbamazepine, free: 0.6 - 4.2 µg/mL

Carbamazepine - epoxide, total: 0.4 - 4.0 µg/mL
Carbamazepine - epoxide, free: 0.2 - 2.0 µg/mL

Billing

CPT codes:

80161 - Carbamazepine epoxide
80156 - Carbamazepine total
80157 - Carbamazepine unbound

Tracking

Date created:

04/16/2015

Revised date:

07/12/2023

Review date:

07/12/2023