Karius Test-994
Restricted to Allina Health infectious disease clinicians
Test info
Provides a non-invasive way to rapidly detect over 1000 pathogens causing both deep-seated and bloodstream infections from a single blood sample.
This is a time sensitive test sent to a third party lab. Other facilities who wish to order a test should work directly with Karius.
Specimen
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting.
- Centrifuge sample within 24 hours of draw at 1600 x g for 10 minutes.
- Transfer plasma to a Screw cap transfer vial/tube (Mayo T914) within 6 hours of collection
- Freeze sample
Frozen (preferred) - 6 months
Ambient - 4 days
- Plasma not separated from whole blood within 24 hours
- Unfrozen sample received more than 4 days after draw
- Specimen with incomplete or improper separations of plasma
Performance
Next-Generation Sequencing (NGS)
Clinical and Interpretive info
Varies per organism: * Reference Interval = the 97.5th percentile MPM concentration detected in PPT plasma from a cohort of 684 asymptomatic donors
MPM (* Molecules Per Microliter = number of DNA fragments present in one microliter of plasma)