Antiphosphatidylserine, IgA, IgG, IgM-994
Test info
An adjunct to β2-glycoprotein and anticardiolipins in diagnosing aPS (antiphospholipid syndrome) for assessing thrombotic risk and other obstetric complications such as miscarriage or fetal growth restriction.
Specimen
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clost
- Spin
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp) labelled as serum, within two (2) hours of sample collection
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
- Gross hemolysis
- Bacterial contamination
- Lipemia
Performance
Enzyme-linked immunosorbent assay (ELISA)
Clinical and Interpretive info
IgM: 0 - 30 MPS
IgA: 0 - 19 APS
IgG: 0 - 30 GPS
High serum levels of antiphospholipid antibodies are frequently detected in patients with autoimmune (ie, SLE) and nonautoimmune diseases, as well as in apparently healthy individuals. These antibodies have been associated with an increased risk for recurrent arterial and venous thrombotic events, thrombocytopenia, and fetal loss.