Alpha Globin Cluster Locus Deletion/Duplication-12674

Test info

  
Alpha Globin Cluster Locus Deletion/Duplication
  
12674
  
LAB12674
  
ALPHA-GLOBUL
  
AGPB
Alpha globin
Alpha thalassemia
Alpha-thalassemia
HBA1
HBA2
Hemoglobin Bart
Hemoglobin-H disease
Hydrops fetalis
ATHAL
  
  • Diagnosis of alpha-thalassemia
  • Prenatal diagnosis of deletional alpha-thalassemia 
  • Carrier screening for individuals from high-risk populations for alpha-thalassemia
  

This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.

Specimen

  
EDTA whole blood
  
  
3.0 mL
  
1.0 mL
  

Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting

  

Lavender (EDTA), 4mL

  
ACD whole blood
  

Yellow ACD (A or B)

 

  

Yellow ACD (A or B)

  

Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

  

Ambient (preferred) - 96 hours

Refrigerated - 96 hours

Prenatal specimens can be sent Mo - Th and must be received by 5 p.m. CST on Friday in order to be processed appropriately.

Performance

  
Mayo Clinic Laboratories (AGDD): R-MM
  
Mo, We
  
9 - 14 days
  

This test is a direct variant analysis assay. Deletions and duplications within the alpha-globin locus are identified by a multiplex ligation-dependent probe amplification assay.

Clinical and Interpretive info

  

An interpretive report will be provided

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81269
  
Yes
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Molecular Medicare Billing Request

Tracking

  
01/26/2017
  
03/11/2025
  
01/02/2024