Thyroglobulin by LCMS-994
Test info
Thryoglobulin (Tg) measurement is intended to aid in monitoring for the presence of orthotopic and/or metastatic thyroid tissues in patients who have had thyroid gland ablation (using thyroid surgery with or without radioactivity). Measurement of thyroglobulin antibody (TgAb) is used to identify patient samples that may be affected by TgAb interference in the measurement of Tg. Quantitative TgAb concentrations can also serve as a surrogate tumor marker for DTC recurrence and for monitoring changes in tumor mass in certain patients.
Specimen
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
Ambient (preferred) - 14 days
Refrigerated - 14 days
- Non-serum sample
Performance
Liquid chromatography with tandem mass spectrometry (LC/MS/MS)
Clinical and Interpretive info
|
Age |
Male (ng/mL) |
Female (ng/mL) |
|
1 – 25 days |
31.6 -101.6 |
33.4 - 169.9 |
|
26 – 31 days |
Not established |
Not established |
|
1 – 23 months |
9.5 - 110.0 |
12.9 - 92.4 |
|
24 months – 7 years |
Not established |
Not established |
|
8 – 10 years |
3.7 - 35.6 |
1.7 - 38.4 |
|
11- 14 years |
3.1 - 23.6 |
3.7 - 31.0 |
|
15 – 17 years |
2.7 - 26.0 |
3.0 - 30.4 |
|
>17 years |
1.4 - 29.2 |
1.5 - 38.5 |