JAK2 V617F mutation detection-7781

Test info

  
JAK2 V617F mutation detection
  
7781
  
LAB7781
  
JAK
  
JAK2
Janus Kinase 2
Tyrosine Kinase mutation
  

Detection of point mutation (G to T mutation in exon 12 resulting in the V to F amino acid change at position 617) of the human JAK2 gene. This mutation is associated with myeloproliferative disorders.

 

Specimen

  
EDTA whole blood
  
  
3.0 mL
  
  • Only ONE (1) tube needs to be drawn for any combination of the following tests:
    • Calreticulin Exon 9 Assay
    • Factor V Leiden Mutation
    • Factor 2 Mutation
    • Hereditary Hemochromatosis
    • JAK2 V617F Mutation Detection
    • MTHFR C677T assay
  • Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting.
  

Lavender (EDTA), 4mL

 

 

  
ACD whole blood
Sodium citrate (Na cit) whole blood
Bone marrow in EDTA
  

Lt blue Sodium citrate (NaCit) - 2.7mL

 

Yellow ACD (A or B)

  

  
3.0 mL
  

Submit specimen in original collection tube, unspun

  

Lt blue Sodium citrate (NaCit) - 2.7mL

Yellow ACD (A or B)

  

Ambient (preferred)

Refrigerated

  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Improper blood/anticoagulant ratio
  • Delay in transport
  • Improper storage
  • Inappropriate timing of collection
  • Interfering substances
  • Leaking container

Performance

  
AHL - Molecular Diagnostics: D
  
Varies
  
7 days
  

Multiplex, Allele-specific Polymerase Chain Reaction (AS-PCR) analyzed by capillary electrophoresis

Clinical and Interpretive info

  

An interpretive report will be included

  

The Calreticulin Exon 9 Assay can be ordered as a reflex to a negative JAK2 V617F Mutation Detection. If ordered as a reflex, do not order the individual assay.

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81270
  
Yes
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

  • Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
  • All information requested is required in order for your request to be completed

Molecular Medicare billing request

Tracking

  
06/28/2006
  
07/27/2018
  
01/15/2024