P2Y12 inhibition-8816

Test info

  
P2Y12 inhibition
  
8816
  
LAB8816
  
P2Y
  
Clopidogrel (Plavix)
Platelet Inhibition
VerifyNow

Specimen

  
Whole blood - P2Y12 collection kit
  
  

Direct venipuncture collection

  1. Using a 21 gauge needle or larger (butterfly is acceptable), collect tubes in the following order:
    1. One (1) clear top Vacutainer tube - partial fill 3 mL draw
    2. Three (3) blue Greiner tubes - These are partial fill 2 mL draw tubes. Fill exactly to the black arrow on the tube; do not over or under fill.
    3. One (1) lavender top tube
  2. Immediatly following collection, thoroughly mix each sample by gently inverting each tube 5 times to prevent clotting
  3. Additional tubes may be collected after these tubes have been collected.


Line draw collection

  1. Discard the first 5 mL of blood from the line.
  2. Ensure the catheter is free of clots.
  3. Immediately transfer blood in the following order:
    1. One (1) clear top Vacutainer tube - partial fill 3 mL draw
    2. Three (3) blue Greiner tubes - These are partial fill 2 mL draw tubes. Fill exactly to the black arrow on the tube; do not over or under fill.
    3. One (1) lavender top tube
  4. Immediatly following addition to the tubes, thoroughly mix each sample by gently inverting each tube 5 times to prevent clotting
  5. Additional tubes may be collected after these tubes have been collected.
  

 

 

  

Aspirin therapy and P2Y12 collection kit/tubes

  

TIME SENSITIVE - Send by STAT courier

Ambient - 4 hours

Hospital Draw - hand deliver to Lab; do not send thru Pneumatic Tube System (PTS).

  
  • Improper labeling (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport
  • Improper storage/transport temperature

Performance

  
AHL - Coagulation: W
Available at the Central Laboratory, Mercy & United
  
Daily - 24 hours
  
1 hour
  

The VerifyNow point-of-care device is available for monitoring patients on anti-P2Y12 therapy (clopidogrel and prasugrel). The extent of ADP-induced platelet aggregation is recorded as the Platelet Reactivity Unit (PRU) value, which is diminished by thienopyridine agents that block the P2Y12 ADP receptor.

Clinical and Interpretive info

  

P2Y12 reaction units (PRU):

Patients on P2Y12 Inhibition therapy : <208
Patients not on P2Y12 Inhibitor medications: 180 - 376

Billing

  
85576

Tracking

  
11/14/2011
  
01/13/2021
  
10/27/2021