N-methyl-D-aspartate receptor antibody, IgG, CSF-994

Test info

  
N-methyl-D-aspartate receptor antibody, IgG, CSF
  
994
  
LAB994
  
MSO
  
Anti-N-methyl-D-Aspartate Receptor (NMDAR), Spinal Fluid
Anti-NMDA CSF
anti-NR1
Glutamate receptor antibodies
N-methyl D-aspartate Ab CSF
NMDA R
NMDAR
NMDA receptor Ab CSF
  

If NMDA antibody IgG is positive, then a NMDA antibody is reported.

  
  • Confirm diagnosis of anti-NMDAR encephalitis.
  • May be used in monitoring treatment response in individuals who are antibody positive.

Specimen

  
Cerebrospinal fluid (CSF)
  
2.0 mL
  
1.0 mL
  

Sterile screw cap vial/tube - 15mL (LabCorp)

  

Ambient (preferred) – 2 weeks

Refrigerated – 2 weeks

Frozen – 2 weeks

Freeze/thaw cycles - stable x3

  
  • Contaminated specimen
  • Hemolysis
  • Severe lipemia

Performance

  
LabCorp (505720): R-NX
  
Su - Sa
  
4 days
  

Immunofluorescence, Immunoblot

Clinical and Interpretive info

  

See report

  

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

Billing

  
86255
86256 (if indicated)

Tracking

  
05/05/2020
  
03/26/2024
  
03/26/2024