Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum-14900

 

 

Test info

  
Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum
  
14900
  
LAB14900
  
MDS2
  
Ataxia
Chorea
Dyskinesias
Myoclonus
Parkinsonism
Brainstem encephalitis
  
Movement Disorder Interp, S
AMPA-R Ab CBA, S
Amphiphysin Ab, S
Anti-Glial Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 2
Anti-Neuronal Nuclear Ab, Type 3
AP3B2 IFA, S
CASPR2-IgG CBA, S
CRMP-5-IgG Western Blot, S
DPPX Ab IFA, S
GABA-B-R Ab CBA, S
GAD65 Ab Assay, S
GFAP IFA, S
GRAF1 IFA, S
IgLON5 IFA, S
ITPR1 IFA, S
KLHL11 Ab CBA, S
LGI1-IgG CBA, S
mGluR1 Ab IFA, S
Neurochondrin IFA, S
NIF IFA, S
NMDA-R Ab CBA, S
P/Q-Type Calcium Channel Ab
Purkinje Cell Cytoplasmic Ab Type 1
Purkinje Cell Cytoplasmic Ab Type 2
Purkinje Cell Cytoplasmic Ab Type Tr
Septin-5 IFA, S
Septin-7 IFA, S

For reflex tests, see algorithm listed on Clinical and Interpretive info Tab
  

 

Evaluating patients with suspected paraneoplastic or other autoimmune movement disorders including patients with ataxia, chorea, dyskinesias, myoclonus, parkinsonism, and stiff-person spectrum in serum specimens

Specimen

  
Serum
  
  
4.0 mL
  
3.0 mL
  

Immediately following collection, mix sample thoroughly by gentle inversion, 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  
  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum, within two (2) hours of sample collection
  

Refrigerated (preferred) – 28 days

Ambient – 72 hours

Frozen – 28 days

  
28 days
  
  • Gross hemolysis
  • Gross lipemia
  • Gross icterus

Performance

  
Mayo Clinic Laboratories (MDS2): R-NX
  
Mo - Su
Reflex tests: Varies
  
8 - 12 days
  

Immunofluorescence Assay (IFA)

Western Blot (WB)

Cell Binding Assay (CBA)

Radioimmunoassay (RIA)

Immunoblot (IB)

Clinical and Interpretive info

  

See report

  
A negative antibody test result does not exclude an autoimmune movement disorder.

Corticosteroid treatment prior to the serum collection may cause a false-negative result.

Intravenous immunoglobulin (IVIg) treatment prior to the serum collection may cause a false-positive result.

Billing

  
86596
86255 x 25
84182
86341

Additional CPT codes (if appropriate):
86255 ITPCS
86256 ITPTS
86256 K11TS
86255 NCDCS
86256 NCDTS
86255 NFHCS
86255 NFLCS
86256 NIFTS
86256 NMDIS
84182 PC1BS
86256 PC1TS
86256 PC2TS
84182 PCTBS
86256 PCTTS
86255 SP5CS
86256 SP5TS
86255 SP7CS
86256 SP7TS
86255 ITPCS
86256 ITPTS
86256 K11TS
86255 NCDCS
86256 NCDTS
86255 NFHCS
86255 NFLCS
86256 NIFTS
86256 NMDIS
84182 PC1BS
86256 PC1TS
86256 PC2TS
84182 PCTBS
86256 PCTTS
86255 SP5CS
86256 SP5TS
86255 SP7CS
86256 SP7TS

Tracking

  
02/22/2022
  
05/01/2023
  
05/01/2023