Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked dominant protoporphyria.

 Specimens smaller than 100 g may not provide interpretable results

• Patient should be instructed to refrain from red meat and aspirin-containing medications for 3 days prior to, as well as during, specimen collection.
• No barium, laxatives, or enemas may be used within 24 hours of starting the collection.

Stool collection kit (Mayo)

• Use as many containers as necessary
• Label all containers X of X (eg. 1 of 2, 2 of 2)

Freeze

Submit all containers

Mayo stool collection jar

• Length of collection period is required
• Include a list of medications the patient is currently taking
• Indicate patient compliance of diet/medications recommendations listed in patient preparation

Frozen (preferred) - 14 days

Refrigerated - 14 days

High-Performance Liquid Chromatography (HPLC)

Porphyrins are quantified by fluorescence

See report