Integrated 1 without NT-13688
Test info
PAPP-A
Screening test for Open Spina Bifida (ONTD), Trisomy 21 (Down syndrome), and Trisomy 18 (Edwards syndrome).
Specimen
- Collect sample between 10.0 and 13.9 weeks of gestation.
- Immediatley following collection, mix sample by gently inverting 5 times
1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection
Pour-off/aliquoting is not advised
Gold serum separator (SST) tube
Ambient (preferred) - 7 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x3
- Gross hemolysis
- Gross lipemia
Performance
Chemiluminescent immunoassay
Clinical and Interpretive info
This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.
Serum integrated screening requires two specimens: one collected in the first trimester and one in the second trimester.
This test number is for the first trimester portion of the test. Result interpretation will be provided only when the second trimester specimen is received and tested.