Antiscleroderma-70 antibodies-13355

Test info

  
Antiscleroderma-70 antibodies
  
13355
  
LAB13355
  
SCL
  
Anti-Scl 70
ANTISCL70M
  

Semiquantitative result of IgG class

  

Differential diagnosis of scleroderma (progressive systemic sclerosis)

Specimen

  
Serum
  
  
1.0 mL
  
0.5 mL
Note: This volume does not allow for repeat testing
  

Spin

  

Gold serum separator (SST) tube

  
  

Spin and separate

  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

  

Hemolysis, icterus, lipemia, gross bacterial contamination

Performance

  
LabCorp Burlington (018705): R-LC
  
Mo - Sa
  
1 - 3 days
  

Multiplex flow immunoassay

Clinical and Interpretive info

  

0.0 - 0.9 AI

  

Scl-70 antibody is seen in 20% of patients with scleroderma, and in some patients with CREST syndrome (calcinosis, Raynaud, esophageal dysfunction, sclerodactyly, telangiectasia). These syndromes are also associated with a high frequency of speckled pattern immunofluorescent antinuclear antibody tests. Scl-70 may identify a subset of scleroderma patients with severe skin, joint, and lung disease. In addition, the presence of Scl-70 in Raynaud phenomenon may indicate a poor prognosis.

Billing

  
86235
  
Result 27416-7

Tracking

  
03/27/2019
  
11/15/2019
  
02/16/2021