Gold serum separator (SST) tube
Refrigerated (preferred) - 7 days
Indirect Fluorescent Antibody (IFA)
Anti-mitochondrial antibodies are present in 85 to 95 %t of cases of primary biliary cirrhosis. The presence of high titers of AMA is helpful in distinguishing biliary cirrhosis from liver problems due to obstruction outside of the liver, viral hepatitis, and alcoholic cirrhosis. Low titers may be detected in other liver disorders including chronic active hepatitis and cryptogenic cirrhosis.
Reflexes to titer if positive.
Screening is perfomed at 1:20 dilution. Titers performed: 1:40, 80, 160, 320 and 640