Alpha-fetoprotein with AFP-L3%-994

July 25, 2022 

LabCorp is currently experiencing testing and reporting delays for this assay.

 

Test info

  
Alpha-fetoprotein with AFP-L3%
  
994
  
LAB994
  
MSO
  
α-Fetoprotein
AFP
  

The AFP-L3% assay is intended for use in the assessment of risk for the development of hepatocellular carcinoma (HCC) in patients with chronic liver diseases.

Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy.

  

Samples from patients with acute hepatitis or fulminant hepatitis can show high values of AFP-L3% and AFP. Pregnancy can cause high values of AFP-L3% and AFP. AFP producing tumors other than HCC can show high values of AFP-L3% and AFP. Bilirubin at a concentration >20 mg/dL can cause a negative influence on the AFP-L3% and AFP values. Glucose at a concentration >600 mg/dL can cause a negative influence on AFP-L3% values. With regard to AFP, normal values apply only to males and nonpregnant females. Normal infants younger than 18 months of age may have higher values.

Results for this test should not be used as absolute evidence of presence or absence of malignant disease without confirmation of the diagnosis by another medically established diagnostic product or procedure. Values obtained with different assay methods or kits cannot be used interchangeably.

Specimen

  
Serum
  
  
0.5 mL
  
0.3 mL
Ii>Submission of the minimum volume does not allow for repeat testing
  

Immediately following collection, mix sample thoroughly by gentle inversion, 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
0.5 mL
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Refrigerated (preferred) - 9 days

Frozen - 9 days

Freeze/thaw cycles - stable x3

Ambient - 9 days

  
  • Gross icterus

Performance

  
LabCorp Burlington (141300): R-NX
  
Mo - Fr
  
4 days
  

Liquid-phase Binding assay

Clinical and Interpretive info

  

AFP, serum *

Age

Male

Female

AFP, Serum

(ng/mL)

AFP, Serum

(ng/mL)

0 – 7 days

0.0–75,265.8

0.0–75,265.8

8 – 30 days

0.0–32,556.4

0.0–32,556.4

1 month

0.0–1,747.8

0.0–1,600.3

2 months

0.0–391.1

0.0–550.0

3 months

0.0–225.8

0.0–339.9

4 months

0.0–230.6

0.0–230.6

5 months

0.0–118.0

0.0–234.0

6 months

0.0–97.2

0.0–97.2

7–11 months

0.0–60.3

0.0–60.3

1 year

0.0–21.4

0.0–21.4

2 years

0.0–9.4

0.0–10.1

3 – 4 years

0.0–5.5

0.0–5.5

5 years

0.0–3.6

0.0–4.2

6 – 12 years

0.0–3.9

0.0–3.9

13 – 17 years

0.0–4.3

0.0–4.3

18 – 30 years

0.0–5.7

0.0–4.7

31 – 50 years

0.0–6.9

0.0–6.4

51 – 80 years

0.0–8.4

0.0–9.2

>80 years

0.0–6.4

0.0–8.7

* Normal values apply only to males and to non-pregnant females. These results are not interpretable for pregnant females.

 

AFP-L3%, serum

0.0 – 9.9

Billing

  
82107
  
Result 42332-7

Tracking

  
06/03/2019
  
04/11/2022
  
03/31/2022