Prolactin, Pituitary Macroadenoma, Serum-994

This is the correct prolactin test to rule-out hook effect and dilutions.

Macroprolactin is different test.

Test info

  
Prolactin, Pituitary Macroadenoma, Serum
  
994
  
LAB994
  
MSO
  
dilutions
rule out hook effect
Prolactin Macroadenoma
  

Useful for quantifying prolactin in serum specimens where the high-dose hook effect is suspected (e.g., presence of pituitary tumor with symptoms of prolactinoma and lower than expected serum prolactin concentration).

  

This test order is restricted to endocrinologists.

Specimen

  

A pituitary adenoma should be identified by imaging studies prior to ordering this tes

  
Serum
  
  
1.5 mL
  
1.0 mL
(Note: This volume does not allow for repeat testing.)
  
  • Draw between 8 a.m. and 10 a.m. (levels subsequently increase).
  • Immediately following collection, mix sample thoroughly by gentle inversion, 5 times
  

1. Allow sample to clot for a minimum of 30 minutes
2. Spin within two (2) hours of sample collection

 

  

Gold serum separator (SST) tube

  
Heparin plasma
  

Red serum vial/tube, 5 mL

Dk green heparin (Li or Na), no gel

 

  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Red: 

  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum

Dk green:

  1. Spin within two (2) hours of sample collection
  2. Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as plasma
  

Refrigerate (preferred) - 14 days

Ambient - 7 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

  

Samples collected in oxalate, EDTA, or citrate plasma

Performance

  
LabCorp (004500); R-NX
  
3-4 days
  

Electrochemiluminescence immunoassay (ECLIA)

Clinical and Interpretive info

  
  • Male: 4.0−15.2 ng/mL
  • Female: 4.8−23.3 ng/mL

Billing

  
84146 x2

Tracking

  
10/02/2023
  
10/02/2023