CD52 Cell Expression Evaluation, Varies-994

Test info

  
CD52 Cell Expression Evaluation, Varies
  
994
  
LAB994
  
MSO
  
Alemtuzumab (Campath) (CD52)
Campath-1H (CD52)
CD52
CEE52
TAE
Therapeutic Antibody Evaluation
  
  • Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD52
  • Determining the eligibility of patients for monoclonal antibody therapies
  • Monitoring response to the therapeutic antibody

Specimen

  
Whole blood or Bone Marrow
  

Yellow ACD (A or B)

 

  
Whole blood: 10 mL
Bone Marrow: 5 mL
  
Whole blood: 3 mL
Bone Marrow: 1 mL
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Send specimen in original tube. Do not aliquot.

  

Yellow ACD (A or B)

 

  
  
Whole blood: 3 mL
Bone Marrow Aspirate: 1 mL
  

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  

Send specimen in original tube. Do not aliquot.

  
  

The following information is required:

  1. The therapeutic monoclonal antibody being used or considered
  2. The pertinent hematologic diseases that have been diagnosed or considered
  3. Specimen source
  

Ambient (preferred) – 4 days

Refrigerated – 4 days

 

Performance

  
Mayo Clinic Laboratories (CEE52): R-NX
  
Mo - Fr
  
1 - 4 days
  

Immunophenotyping

Clinical and Interpretive info

  

The immunophenotyping report will summarize the pattern of antigenic expression on malignant cells and, if appropriate, the normal cellular counterparts that correspond to the therapeutic monoclonal antibody target.

Billing

  
88184
88185 x3
88187

Tracking

  
03/22/2023
  
03/22/2023