Alpha-fetoprotein (AFP), maternal serum-13494

Test info

  
Alpha-fetoprotein (AFP), maternal serum
  
13494
  
LAB13494
  
AFPB
  
AFP, maternal serum for Open Spina Bifida
AFP, Maternal Serum
Alpha-Fetoprotein,Maternal Serum for Open Spina Bifida
Maternal Serum Alpha-Fetoprotein
  

Screening test for open neural tube defects. Detects 80% of open spina bifida and 90% of anencephaly.

 

  

This test does not provide screening for Down syndrome or trisomy 18.

Specimen

  

Open spina bifida screening is offered for gestational ages 15.0 - 23.9 weeks (optimal gestational age is 16.0 - 18.9 weeks.)

  
Serum
  
  
3.0 mL
  
0.5 mL
  

Specimens must be collected before amniocentesis.

Collect in serum separator tube with gel barrier.

  
  1. Allow blood to clot, avoiding hemolysis
  2. Separate serum from cells by centrifugation

   Pour off is not advised.

  

Gold serum separator (SST) tube

  
  

Ambient (preferred) - 7 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x 3

  
  • Gross hemolysid
  • Gross lipemia
  • Quantity not sufficient for analysis (QNS) 
  • Improper specimen type

Performance

  
LabCorp RTP (010801): R-LC
  
Mo - Sa
  
2 - 6 days
  

Chemiluminescent immunoassay

Clinical and Interpretive info

  

An interpretive report will be provided

  

A positive result means that more diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect is present.

Billing

  
82105
  
Yes
  
  
Result UNLOINC

Tracking

  
04/08/2019
  
10/25/2019
  
02/12/2021