BCL2/IGH by FISH-4280J (malignant tissue)

Test info

  
BCL2/IGH by FISH
  
4280J (malignant tissue)
  
LAB4280J - CYTOGENETICS MALIGNANT TISSUE STUDIES
  
CG BCL2/IGH or BCL2/IGH
  
BCL2/IGH
Diffuse Large B-Cell Lymphoma
FISH
Fluorescence in Situ Hybridization
Follicular lymphoma
High Grade B-Cell Lymphoma
t(14;18)
14q32
18q21
  

BCL2/IGH rearrangements are associated with Follicular lymphoma and can help differentiate diffuse Large B-cell lymphoma from High-grade lymphoma.

This test can be ordered individually or as part of a High Grade B-cell Lymphoma FISH Panel. See the panel test for details.

Specimen

  
Solid Tumor or aspirate/Lymph Node (fresh tissue)
  

Sterile cup or tube

  
5 mm3 tissue
5 mL
  

Place specimen in a sterile cup/tube with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.

  

Submit entire fresh specimen.

  

Sterile specimen cup/tube

  
Paraffin embedded tissue
Slides
Touch prep slides
  
Paraffin block
Three 4-micron cut slides and one H&E stained slide
Touch prep slides
  

Note: Heavy metal fixatives are unacceptable.

  

AHL Cytogenetics Oncology Request

  

Ambient

  
Slides - 6 months
Blocks will be returned post reporting
  
  • Improper label (unlabeled or mislabeled)
  • Slides broken beyond repair
  • Heavy metal fixatives are unacceptable

Performance

  
AHL - Cytogenetics: X
  
Mo - Fr
  
5 business days
  

Fluorescence in situ hybridization (FISH)

Clinical and Interpretive info

  

Normal or Abnormal with interpretation

Billing

  
Paraffin:
88366 x 2
Fresh Tissue/Touch Prep:
88271 x 2
88275
88291
  
Yes
  

Medical necessity

Tracking

  
03/26/2021
  
09/23/2022