B cell gene rearrangement-5453

Test info

B cell gene rearrangement
IgH Rearrangement

Detection of clonal rearrangements of immunoglobulin heavy chain genes that are associated with malignant processes.


EDTA whole blood
4.0 mL
2.0 mL

Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting


Lavender (EDTA), 4mL,


4.0mL ACD whole blood
4.0mL Na Citrate whole blood
5.0cc bone marrow in EDTA
200mg FFPE tissue (B3/B5 not recommended)

Yellow ACD (A or B)


Lt blue Sodium citrate (NaCit)


Bone Marrow

Lavender (EDTA), 4mL





Whole blood 4.0mL (minimum 1.0 mL)
Bone marrow 5.0cc (minimum 1.0cc)
Tissue 200mg

Whole blood/bone marrow

  • Submit entire specimen


  • Frozen preferred if not tested immediately
  • Freeze as quickly as possible at -20 to -70°C
  • Fresh tissues may be submitted in RPMI
  • Best results when used within 3 days
  • Recommended for tissues with high probability of immediate or pending orders
  • Formalin fixed tissue in a paraffin block (B3 and B5 fixatives are not recommended)

Questions call (612) 863-4475


Yellow ACD (A or B)

Lt blue Sodium citrate (NaCit)


RPMI with Hepes/Pen strep/FBS -15 mL

Formalin-fixed, paraffin embedded (FFPE) tissue block


Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

  • Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
  • All information requested is required in order for your request to be completed

Whole blood or bone marrow

Refrigerated (preferred) 

Ambient (OK)



  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Improper blood/anticoagulant ratio
  • Delay in transport
  • Improper storage
  • Inappropriate timing of collection
  • Interfering substances
  • Leaking container
  • Slides broken beyond repair


AHL - Molecular Diagnostics: D
8 days

PCR and Capillary electrophoresis

Clinical and Interpretive info


This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.