Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects
The patient's gestational age must be at least 12 weeks for interpretation of alpha-fetoprotein. AChE false-positive and false-negative results are more frequent at gestational ages less than 13 weeks.
Do not use urine containers or tubes with rubber stoppers, as rubber is toxic to amniocytes.
Avoid contamination of amniotic fluid with maternal or fetal blood. As little as one drop of fetal blood can cause false-positive results during assay of amniotic fluid.
An interpretive report will be provided