Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Spinal Fluid-14901

Test info

  
Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Spinal Fluid
  
14901
  
LAB14901
  
MDC2
  
Ataxia
Chorea
Dyskinesias
Myoclonus
Parkinsonism
Brainstem encephalitis
  
Movement Disorder Interp, CSF
AMPA-R Ab CBA, CSF
Amphiphysin Ab, CSF
Anti-Glial Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 2
Anti-Neuronal Nuclear Ab, Type 3
AP3B2 IFA, CSF
CASPR2-IgG CBA, CSF
CRMP-5-IgG Western Blot, CSF
DPPX Ab IFA, CSF
GABA-B-R Ab CBA, CSF
GAD65 Ab Assay, CSF
GFAP IFA, CSF
GRAF1 IFA, CSF
IgLON5 IFA, CSF
ITPR1 IFA, CSF
KLHL11 Ab CBA, CSF
LGI1-IgG CBA, CSF
mGluR1 Ab IFA, CSF
Neurochondrin IFA, CSF
NIF IFA, CSF
NMDA-R Ab CBA, CSF
Purkinje Cell Cytoplasmc Ab Type Tr
Purkinje Cell Cytoplasmic Ab Type 1
Purkinje Cell Cytoplasmic Ab Type 2
Septin-5 IFA, CSF
Septin-7 IFA, CSF

For reflex tests, see algorithm listed on Clinical and Interpretive info Tab
  

 

Evaluating patients with suspected paraneoplastic or other autoimmune movement disorders including patients with ataxia, brainstem encephalitis, chorea, dyskinesias, myoclonus, and parkinsonism using serum specimens

Specimen

  
Cerebrospinal fluid (CSF)
  

Sterile vial/container

  
4.0 mL
  
3.5 mL
  

Sterile vial/container

  

Refrigerated (preferred) – 28 days

Ambient – 72 hours

Frozen – 28 days

  
28 days
  
  • Gross hemolysis
  • Gross lipemia
  • Gross icterus

Performance

  
Mayo Clinic Laboratories (MDC2): R-NX
  
Mo - Su
Reflex tests: Varies
  
8 - 12 days
  

Immunofluorescence Assay (IFA)

Western Blot (WB)

Radioimmunoassay (RIA)

Cell-Binding Assay (CBA)

Immunoblot (IB)

Clinical and Interpretive info

  

See report

  
A negative antibody test result does not exclude an autoimmune movement disorder.

Corticosteroid treatment prior to the serum collection may cause a false-negative result.

Intravenous immunoglobulin (IVIg) treatment prior to the serum collection may cause a false-positive result.

Billing

  
86255 x 25
84182
86341

Additional CPT codes (if appropriate):

84182-AGNBC
86256-GNTC
86255-AINCC
84182-AMIBC
86256-AMPIC
84182-AN1BC
86256-AN1TC
84182-AN2BC
86256-AN2TC
86256-AN3TC
86255-APBCC
86256-APBTC
86256-APHTC
86256-CRMTC
86255-DPPCC
86256-DPPTC
86256-GABIC
86255-GFACC
86256-GFATC
86255-GL1CC
86256-GL1TC
86255-GRFCC
86256-GRFTC
86255-IG5CC
86256-IG5TC
86255-ITPCC
86256-ITPTC
86256-K11TC
86255-NCDCC
86256-NCDTC
86255-NFHCC
86255-NFLCC
86256-NIFTC
86256-NMDIC
84182-PC1BC
86256-PC1TC
86256-PC2TC
84182-PCTBC
86256-PCTTC
86255-SP5CC
86256-SP5TC
86255-SP7CC
86256-SP7TC

Tracking

  
02/22/2022
  
05/01/2023
  
05/01/2023