Anti-cN-1A Ab (NT5c1A) IBM (RDL)-994

Test info

  
Anti-cN-1A Ab (NT5c1A) IBM (RDL)
  
994
  
LAB994
  
MSO
  
Anti-IBM
IBM
Inclusion body myopathy
MUP44 AB
nt5c1a
sIBM
Sporadic IBM
  

Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.

Specimen

  
Serum
  
  
2.0 mL
  
0.5 mL
(Note: This volume does not allow for repeat testing.)
  

Immediatley following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within one (1) hour of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within one (1) hour of collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  
  

Refrigerated (preferred) - 14 days

Ambient - 7 days

Frozen - 60 days

Freeze/thaw cycles - stable x1

  
  • Grossly hemolyzed
  • Bacterial contamination
  • Lipemic specimen
  • Icteric specimen
  • Non-serum specimen types

Performance

  
LabCorp (520061): R-NX
  
Once per week
  
7 - 10 days
  

Enzyme-linked immunosorbent assay (ELISA)

Clinical and Interpretive info

  

Negative: <20

 

Billing

  
83516

Tracking

  
08/18/2020
  
08/16/2023
  
08/16/2023