Anti-cN-1A Ab (NT5c1A) IBM (RDL)-994

Test info

  
Anti-cN-1A Ab (NT5c1A) IBM (RDL)
  
994
  
LAB994
  
MSO
  
Anti-IBM
IBM
Inclusion body myopathy
MUP44 AB
nt5c1a
sIBM
Sporadic IBM
  

Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.

Specimen

  
Serum
  
  
2.0 mL
  
0.5 mL
  

Immediatley following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within one (1) hour of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin to separate serum from cells and transfers serum to a Transfer vial/tube with cap - 12mL (LabCorp) labelled as "serum" within one (1) hour of sample collection
  
  

Refrigerated (preferred) - 14 days

Ambient - 7 days

Frozen - 60 days

  
  • Grossly hemolyzed
  • Bacterial contamination
  • Lipemic specimen
  • Icteric specimen
  • Non-serum specimen types

Performance

  
LabCorp (520061): R-NX
  
Once per week
  
14 - 21 days
  

Enzyme-linked immunosorbent assay (ELISA)

Clinical and Interpretive info

  

Negative: <20

 

Billing

  
83520

Tracking

  
08/18/2020
  
08/18/2020