Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.
Spin to separate serum from cells within one hour of collection.
Gold serum separator (SST) tube
Spin to separate serum from cells and transfers serum to a Transfer vial/tube with cap - 12mL (LabCorp) within one hour of collection.
Refrigerated (preferred) - 14 days
Ambient - 7 days
Frozen - 60 days
Enzyme-linked immunosorbent assay (ELISA)