Alpha-gal meat allergy panel-994

Test info

  
Alpha-gal meat allergy panel
  
994
  
LAB994
  
MSO
  
Allergen
  
  • Galactose-alpha-1,3 galactose (Alpha-Gal)
  • IgE, Beef (Bos spp)
  • IgE, Pork (Sus spp)
  • IgE, Lamb/Mutton (Ovis spp)
  

Measurement of IgE to galactose alpha-1,3-galactose (α-Gal sIgE) is used in the differential diagnosis of α-Gal mediated allergy. There are two distinct forms of this allergy: the first is an immediate-onset anaphylaxis observed following intravenous infusion of Cetuximab, a monoclonal antibody against epidermal growth factor receptor, and the second is a delayed-onset allergy or anaphylaxis that occurs several hours following consumption of red meat. Bites from certain ticks, such as the Lone Star Tick in the United States, have been implicated in the development α-Gal allergy. Furthermore, α-Gal may be helpful in elucidating the allergen responsible in patients initially diagnosed as having ‘idiopathic’ anaphylaxis or urticaria.

Specimen

  
Serum
  
  
0.5 mL
  

Immediatley following collection, mix sample by inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 3 months

Freeze/thaw cycles - stable x3

 

Performance

  
LabCorp (650003): R-NX
  
5 days
  

ImmunoCAP® , Solid phase Immunoassay

Clinical and Interpretive info

  

An interpretive report will be provided

Billing

  
82785
86008
86003 x 3
  
Yes
  
  
Result 6039-2

Tracking

  
06/03/2019
  
12/14/2021
  
03/16/2022