Birdshot chorioretinopathy (BSCR) is a rare form of autoimmune uveitis that can lead to severe visual impairment. Greater than 95% of patients diagnosed with BSCR carry the human leukocyte antigen (HLA)A*29 allele of the major histocompatibility complex (MHC). The MHC family of genes code for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T cell receptors to elicit an immune response.

Lavender (EDTA), 10mL

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

Lavender (EDTA), 10mL

Two (2) Lavender (EDTA), 4mL

Two (2) Lavender (EDTA), 4mL

Ambient (strict) – 7 days

Frozen – NO

Refrigerated - NO

• Hemolysis
• Clotted specimen

Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution.

See report

The presence of HLA A*29 alone is not sufficient for a diagnosis of Birdshot Chorioretinopathy. Many individuals with HLA A*29 do not have the disease and some patients with the disease do not have HLA A*29.

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

• Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
• All information requested is required in order for your request to be completed

Molecular Medicare billing request