Strep pneumoniae antigen-7764

Test info

Strep pneumoniae antigen
Strep pneumoniae Ag
Streptococcus pneumoniae antigen
Streptococcus meningitis

Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and is often implicated in community-acquired pneumonia of unknown etiology. Pneumococcal pneumonia can lead to bacteremia, meningitis and other potentially life-threatening sequelae. Blood cultures are positive in only 25% of the patients with pneumococcal pneumonia. The Streptococcus pneumoniae Antigen test detects 78% of the non-bacteremic pneumococcal pneumonia cases.

Pneumococcal meningitis can arise spontaneously or can occur as a complication of another pneumococcal infection. It frequently leads to permanent brain damage and the mortality rate is 20-30%. Since it can progress from mild symptoms to a coma stage within hours, rapid diagnosis and treatment is essential.

This test is for the detection of Streptococcus pneumoniae antigen in the urine of patients (≥ 5 years of age) with pneumonia and in the cerebral spinal fluid of patients (any age) with meningitis.

It is intended, in conjunction with culture and other methods, to aid in the diagnosis of both pneumococcal pneumonia and pneumococcal meningitis.


Cerebrospinal fluid (CSF) - for diagnosis of meningitis in patients of any age

Sterile vial/container

1.0 mL
150 µL

Sterile vial/container


Urine, random - for diagnosis of pneumonia in adults and children ≥ years of age

Urine can be submitted in the collection container, or, if volume is sufficient transferred to a Urine preservative vial/tube, C&S

Urine processing instructions (BD)


Urine preservative vial/tube, C&S

or Screw capped plastic container (sterile)



Refrigerated (preferred) - 7 days

Ambient - 24 hours

Frozen - 7 days


Refrigerated (preferred) - 14 days

Ambient - 24 hours

Frozen - 14 days

  • Improper label (unlabeled or mislabeled)
  • Time delay between time of collection and receipt of specimen
  • Improper transport container
  • Improper transport temperature
  • Interfering substances
  • Leaking container
  • Specimens other than urine or CSF
  • Specimen at room temperature longer than 24 hours
  • Urine refrigerated or frozen longer than 14 days
  • Urine specimens from children <5 yr of age
  • CSF refrigerated or frozen (-20˚ C) longer than 7 days
  • CSF frozen at less than -20˚ C



AHL - Microbiology: M
2 hours after receipt

Immunochromatographic assay

Clinical and Interpretive info


Presumptive negative (see report)