Fluconazole, serum or plasma-994

Test info

  
Fluconazole, serum or plasma
  
994
  
LAB994
  
MSO
  
Diflucan
  

Treatment of candidiasis, cryptococcal meningitis, and antifungal prophylaxis in allogeneic bone marrow transplant recipients.

Specimen

  
Serum
  
  
1.0 mL
  
0.5 mL
  
  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  
EDTA plasma
  
  

Immediatley following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

  
  1. Spin within two (2) hours of sample collection
  2. Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as EDTA plasma
  

Transfer vial/tube with cap - 12mL (LabCorp)

  

Refrigerated (preferred) - 14 days

Ambient - 14 days

Frozen - 14 days

  
  • Serum from gel-barrier tubes is not acceptable and will be rejected

Performance

  
LabCorp Burlington (700485): R-NX
  
Mo - Fr
  
3 - 7 days
  

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Clinical and Interpretive info

  
The average peak concentration in fasted patients one to two hours after administration of a single oral 400mg dose of Fluconazole was 6.72 µg/mL (range 4.12 - 8.08).
 
No relationship between plasma concentrations and efficacy or toxicity has been identified for Fluconazole, however, exposure may be altered in instances of renal dysfunction or renal replacement therapy.

Billing

  
80299
  
Result 10987-6

Tracking

  
10/09/2019
  
10/14/2019
  
12/27/2023