Coxsackie A virus antibody profile, IgG, IgM-13536

Test info

  
Coxsackie A virus antibody profile, IgG, IgM
  
13536
  
LAB13536
  
COXAB
  
Hand, foot & mouth disease
  

This assay uses indirect immunofluorescence to determine IgG and IgM titers to Coxsackie A serotypes A7, A9, A16, and A24. Recent infections of Coxsackie viruses are characterized by elevated titers of IgG and IgM.

Specimen

  
Serum
  
  
1.0 mL
  
0.5 mL
Submission of the minimum volume does not allow for repeat testing
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x 3

  
  • Microbially-contaminated or heat-treated specimen
  • Specimen containing particulate matter
  • Grossly hemolyzed, lipemic, or icteric samples

Performance

  
LabCorp Burlington (163295): R-LC
  
Mo - Fr
  
2 - 5 days
  

Indirect fluorescent antibody (IFA)

Clinical and Interpretive info

  
IgG
Coxsackie A7 - Neg: < 1:100
Coxsackie A9 - Neg: < 1:100
Coxsackie A16 - Neg: < 1:100
Coxsackie A24 - Neg: < 1:100
 
IgM
Coxsackie A7 - Neg: < 1:10
Coxsackie A9 - Neg: < 1:10
Coxsackie A16 - Neg: < 1:10
Coxsackie A24 - Neg: < 1:10
  

Coxsackie viruses are enteroviruses belonging to the Picornavirus family, which is comprised of strains A and B as well as various serotypes A1-22, 24, and B1-6. Following incubation, a variety of well known diseases can manifest themselves within the host.  Coxsackie A is commonly associated with hand, foot, and mouth disease, which primarily affects children younger than 10 years of age. In rare cases, Coxsackie infections may produce mild or subclinical symptoms, yet most infections trigger the onset of flu-like ailments but may include symptoms of other diseases along the lines of pneumonia, hepatitis, and meningitis.

Billing

  
86658 x 8
  
Result 59584-3

Tracking

  
03/29/2019
  
05/20/2019
  
12/31/2023