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Paraneoplastic autoantibody evaluation, CSF-14306

Test info

Test name:

Paraneoplastic autoantibody evaluation, CSF

Test number:

14306

Excellian order number:

LAB14306

Abbreviation:

PAC1

Alternate names:

Anti-Hu
Antineuronal
Cerebellar antibodies
Dorsal root ganglion antibody

Tests included:

Paraneoplastic Interpretation, CSF
Anti-Neuronal Nuclear Ab, Type 1
Anti-Neuronal Nuclear Ab, Type 2
Anti-Neuronal Nuclear Ab, Type 3
Anti-Glial Nuclear Ab, Type 1
Purkinje Cell Cytoplasmic Ab Type 1
Purkinje Cell Cytoplasmic Ab Type 2
Purkinje Cell Cytoplasmc Ab Type Tr
Amphiphysin Ab, CSF
CRMP-5-IgG, CSF

Useful for:

An aid in the diagnosis of paraneoplastic neurological autoimmune disorders related to carcinoma of lung, breast, ovary, thymoma, or Hodgkin's lymphoma
In patients with a history of tobacco use or other lung cancer risk, or if thymoma is suspected, Paraneoplastic autoantibody evaluation, serum is also recommended.

Specimen

Specimen type:

Cerebrospinal fluid (CSF)

Volume:

4.0 mL

Minimum volume:

2.0 mL

Processing instructions:

Do not spin; submit entire specimen

Transport container:

Screw-capped polypropylene vial/tube, sterile (Mayo)

Transport and stability:

Refrigerated (preferred) - 28 days

Ambient - 72 hours

Frozen - 28 days

Performance

Performing lab:

Mayo Clinic Laboratories (PAC1): R-NX

Days set up:

Daily

TAT:

3 - 4 days if Negative;5 - 8 days if Positive

Method:

Immunofluorescence Assay (IFA), Radioimmunoassay, Cell-Binding Assay (CBA) and Western Blot

Clinical and Interpretive info

Reference ranges:

Negative at < 1:2

Billing

CPT codes:

86255 x 9

Additional CPT codes (if appropriate):
83519
84182 x 7
86255 x 9
86256 x 5
86341

Tracking

Date created:

06/05/2013

Revised date:

05/19/2020