Anti-Jo-1-13408
Test info
Anti-Jo-1
13408
LAB13408
JO1
Polymyositis
t-RNA synthetase
t-RNA synthetase
Evaluate patients suspected of having polymyositis, dermatomyositis, or polymyositis-scleroderma overlap syndrome.
Specimen
Serum
0.6 mL
0.3 mL
Immediatley following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x 3
- Hemolysis
- Icterus
- Lipemia
- Bacterial contamination
Performance
LabCorp Burlington (161455): R-LC
Mo - Sa
1 - 3 days
Multiplex flow immunoassay
Clinical and Interpretive info
0.0 - 0.9 AI
Anti-Jo-1 antibodies are present in approximately 20% to 30% of patients with adult-onset polymyositis syndromes. They are present in >65% of patients with both myositis and interstitial lung disease. In such patients, the presence of anti-Jo-1 antibodies may be predictive of a response to steroid treatment. Testing for ANAs is not adequate for the detection of anti-Jo-1 antibodies.
Billing
86235
Result 11565-9
Tracking
03/27/2019
03/29/2021
12/31/2023