HLA B51 disease association-994

Test info

  
HLA B51 disease association
  
994
  
LAB994
  
MSO
  
B*51:01
B51
Behcet
Behcet Disease
Behcet's Disease, HLA B*51:01
HLA B51
  

Behcet Disease (BD) is a rare, chronic, multisystem disease caused by vasculitis of blood vessels throughout the body. The disease course is marked by recurrent ulcers of the oral and genital regions, often with severe ocular inflammation that may lead to visual impairment or blindness. This disease is found most often in individuals that carry the HLA B*51 allele of the major histocompatibility complex (MHC). HLA B*51 is the predominant risk factor for BD in all populations studied, however not all BD patients carry the B*51 allele. The disease is prevalent in countries in the eastern Mediterranean, the Middle East, and East Asia and in individuals of Middle Eastern, Far Eastern and Mediterranean decent.

Specimen

  
EDTA whole blood
  
  
7 mL
  
3.0 mL
  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

  

Lavender (EDTA), 4mL

  

Ambient - 90 days

  
  • Hemolysis
  • Clotted sample
  • Wrong specimen container

Performance

  
LabCorp Burlington (167389): R-NX
  
Daily
  
3 - 7 days
  

Sequence-based typing (SBT), sequence-specific oligonucleotide probes (SSOP), and/or sequence-specific primers (SSP) as needed to obtain the required resolution

Clinical and Interpretive info

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81373
  
Yes
  

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

  • Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
  • All information requested is required in order for your request to be completed

Molecular Medicare billing request

Tracking

  
05/20/2019
  
06/22/2023
  
12/26/2023