Antichromatin antibodies-994

Test info

  
Antichromatin antibodies
  
994
  
LAB994
  
MSO
  
Antibodies to LE cell
  

Help to diagnose drug-induced lupus (DIL) and systemic lupus erythematosus (SLE).

Antibodies to both chromatin and histones have been found in patients with procainamide-induced lupus; however, patients with lupus induced by drugs such as quinidine, penicillamine, methyldopa, and acebutolol have antibodies to chromatin but not antihistone. Antichromatin antibodies are found in 50% to 90% of SLE patients and have been linked with proteinuria in SLE patients.

Specimen

  
Serum
  
  
1.0 mL
  
0.5 mL
Submission of the minimum volume does not allow for repeat testing
  

Immediatley following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

  
  • Hemolysis

Performance

  
LabCorp Burlington (012580): R-NX
  
Mo - Sa
  
4 days
  

Multiplex flow immunoassay

Clinical and Interpretive info

  

0.0 - 0.9 AI

Billing

  
86235
  
Result 51775-5

Tracking

  
06/03/2019
  
03/17/2022
  
03/17/2022