Beta F1 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test info

  
Beta F1 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
Beta framework
BF-1
  
  • All IHC stains will include a positive control tissue
  
  • Useful in identifying alpha-beta T-cell receptors from T-cell clones or polyclonal populations of T-cells
  • Aids in diagnosing T-cell lineage neoplasms

Specimen

  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

Tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair

Performance

  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

Clinical and Interpretive info

  

If requested, an interpretive report will be provided

  

Specifications

  • Recognizes T-cell receptor (TCR) beta subunit, that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules
  • TCR is composed of a heterodimer; 95% of T cells this consists of an alpha and beta chain and 5% of T cells this consists of gamma and delta chains

 Staining pattern

  • Cytoplasmic

References

  1. Ohshima K et al: Virchows Arch. 1999 Aug;435(2):92-100.

Billing

  
88342 - 1st stain
88341 - each additional stain

Tracking

  
10/30/2017
  
10/17/2018
  
01/12/2024