Collapsin response-mediator protein-5-IgG, Western blot, serum-994

Test info

  
Collapsin response-mediator protein-5-IgG, Western blot, serum
  
994
  
LAB994
  
MSO
  
Chorea
Vision loss
Cranial neuropathy
CRMP5
Myelopathy
  

Evaluation of cases of chorea, vision loss, cranial neuropathy and myelopathy

Specimen

  
Serum
  
  
1.5 mL
  
1.0 mL
  

Immediately following collection, mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a  Screw cap transfer vial/tube (Mayo T465), labelled as serum, within two (2) hours of sample collection
  
  

Refrigerated (preferred) – 28 days

Ambient – 72 hours

Frozen – 28 days

  
28 days
  
  • Gross hemolysis
  • Gross icterus
  • Gross lipemia

Performance

  
Mayo Clinic Laboratories (CRMWS): R - NX
  
Mo - Th; 8 a.m.
  
5 – 10 days
  

Western blot

Clinical and Interpretive info

  

Negative

  

A positive result confirms that a patient's subacute neurological disorder has an autoimmune basis, and is likely to be associated with a small-cell lung carcinoma (SCLC) or thymoma, which may be occult. A positive result has a predictive value of 90% for neoplasm (77% SCLC, 6% thymoma). Seropositivity is found in approximately 3% of patients who have SCLC with limited metastasis without evidence of neurological autoimmunity.

Billing

  
84182
  
47401-5

Tracking

  
04/28/2021
  
04/28/2021