Collapsin response-mediator protein-5-IgG, Western blot, serum-994
Test info
Collapsin response-mediator protein-5-IgG, Western blot, serum
994
LAB994
MSO
Chorea
Vision loss
Cranial neuropathy
CRMP5
Myelopathy
CRMP-5
CV2
Vision loss
Cranial neuropathy
CRMP5
Myelopathy
CRMP-5
CV2
Evaluation of cases of chorea, vision loss, cranial neuropathy and myelopathy
Specimen
Serum
1.5 mL
1.0 mL
Immediately following collection, mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot
- Spin within two (2) hours of sample collection
- Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
Refrigerated (preferred) – 28 days
Ambient – 72 hours
Frozen – 28 days
28 days
- Gross hemolysis
- Gross icterus
- Gross lipemia
Performance
Mayo Clinic Laboratories (CRMWS): R - NX
Mo - Th; 8 a.m.
5 – 10 days
Western blot
Clinical and Interpretive info
Negative
A positive result confirms that a patient's subacute neurological disorder has an autoimmune basis, and is likely to be associated with a small-cell lung carcinoma (SCLC) or thymoma, which may be occult. A positive result has a predictive value of 90% for neoplasm (77% SCLC, 6% thymoma). Seropositivity is found in approximately 3% of patients who have SCLC with limited metastasis without evidence of neurological autoimmunity.
Billing
84182
47401-5
Tracking
04/28/2021
01/02/2024