Alpha-globin gene analysis-12674

Mayo Clinic Laboratories has announced due to technical limitations, this assay will no longer include the two non-deletional mutations Constant Spring and alphaT Saudi.

A new supplemental method to detect these two variants will be added in the near future.

Test info

  
Alpha-globin gene analysis
  
12674
  
LAB12674
  
ALPHA-GLOBUL
  
AGPB
Alpha globin
Alpha thalassemia
Alpha-thalassemia
Constant Spring
HBA1
HBA2
Hemoglobin Bart
Hemoglobin-H disease
Hydrops fetalis
Saudi
  
  • Diagnosis of alpha-thalassemia
  • Prenatal diagnosis of deletional alpha-thalassemia 
  • Carrier screening for individuals from high-risk populations for alpha-thalassemia

Specimen

  
EDTA whole blood
  
  
3.0 mL
  
1.0 mL
  

All prenatal specimens must be accompanied by a maternal blood specimen.
Order MATCC / Maternal Cell Contamination, Molecular Analysis on the maternal specimen.

  

Lavender (EDTA), 4mL

  
ACD whole blood
Heparin whole blood
  

Yellow ACD (A or B)

 

Dk green heparin (Li or Na), no gel

 

 

  
3.0 mL
  

Yellow ACD (A or B)

Dk green heparin (Li or Na), no gel

  

Molecular Medicare billing request

  • Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
  • All information requested is required in order for your request to be completed
  

Ambient (preferred) - 96 hours

Refrigerated - 96 hours

Prenatal specimens can be sent Mo - Th and must be received by 5 p.m. CST on Friday in order to be processed appropriately.

Performance

  
Mayo Clinic Laboratories (ATHAL): R-MM
  
2x/week
  
12 - 14 days
  

Dosage Analysis by Polymerase Chain Reaction (PCR)/Multiplex Ligation-Dependent Probe Amplification (MLPA)/Luminex Technology

Clinical and Interpretive info

  

An interpretive report will be provided

Billing

  
This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.
  
81269
  
Yes
  

Tracking

  
01/26/2017
  
11/08/2018
  
02/24/2020