Only one specimen tube is required to perform all ordered cytogenetics testing.
The more testing requested, the closer to the optimal volume requirements is preferred
Dk green Sodium heparin (Na hep), no gel
Lavender (EDTA), 4mL
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation
Although not listed in the NCCN cytogenetics prognostic table, it is recommended to rule out a t(11;14) in CLL patients.
In Plasma Cell Myeloma, a t(11;14) is classified as a standard cytogenetics risk factor by mSMART 3.0